Xanthines as a scaffold for molecular diversity

A carbohydrate binding module as a diversity-carrying scaffold.

The growing field of biotechnology is in constant need of binding proteins with novel properties. Not just binding specificities and affinities but also structural stability and productivity are important characteristics for the purpose of large-scale applications. In order to find such molecules, libraries are created by diversifying naturally occurring binding proteins, which in those cases s...

Decellularized kidney in the presence of chondroitin sulfate as a natural 3D scaffold for stem cells

Objective(s): Use of biological scaffolds and automating the cells directing process with materials such as growth factors and glycosaminoglycans (GAGs) in a certain path may have beneficial effects in tissue engineering and regenerative medicine in future. In this research, chondroitin sulfate sodium was used for impregnation of the scaffolds. It is a critical component in extracellular matrix...

P48: Self-Assembling Peptide Nanostructures as a Good Scaffold for Treatment of Spinal Cord Injury

لطفاً به چکیده انگلیسی مراجعه شود.

Scaffold Diversity of Fungal Metabolites

Many drug discovery projects rely on commercial compounds to discover active leads. However, current commercial libraries, with mostly synthetic compounds, access a small fraction of the possible chemical diversity. Natural products, in contrast, possess a vast structural diversity and have proven to be an outstanding source of new drugs. Several chemoinformatic analyses of natural products hav...

Tetrameric Cyclic Double Helicates as a Scaffold for a Molecular Solomon Link**